The EAA™ dose response is an exponential curve, characterized by two asymptotes. The two asymptote regions are the high and low non measurable regions of the curve. Recent data suggests that PMX works best on patients with EAA results of ≥0.60 and <0.90. The efficacy of the product has not been demonstrated for patients with EAA levels ≥0.9. Care should be taken when interpreting EAA results greater than 0.9 as small differences in EAA values correlate to large differences in endotoxin concentration due to the asymptote at EAA value 1.0.

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