For Researchers

EAA™ Dose Response


EAA™ and PMX are licensed and available for use in Canada. PMX is not approved for clinical use in the USA, and is currently undergoing the PMA (Premarket approval) process. EAA™ is FDA cleared for use in the USA. The information presented herein is region specific. Please contact Spectral Medical Inc. at to obtain appropriate product information for your country.

The EAA dose response is an exponential curve characterized by two asymptotes. The EAA generates a unit less number, called endotoxin activity, which correlates to the concentration of endotoxin in the sample. Below is a representative dose response for E. coli O55:B5 endotoxin. The shape of the curve changes slightly depending on the species of bacteria the endotoxin is derived from. Further, Spectral is available to provide a variety of EAA reagents to research customers in order to allow customization of the assay to specific research needs, such as different animal studies. For more information and specific dose response information, contact us at

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