PMX (Toraymyxin hemoperfusion) is a Polymyxin B extracorporeal direct hemoperfusion adsorption column which is highly effective in removing endotoxin in the bloodstream. PMX has been approved and marketed by Toray Industries in Europe and Japan since 2002 and 1994 respectively, and has been used safely on more than 150,000 patients. Spectral has conducted a Phase III clinical trial for severe sepsis and septic shock in North America and has submitted a PMA to gain FDA approval for the distribution of PMX in USA where Spectral holds the exclusive licencing rights. PMX is available in Canada where Spectral holds the exclusive rights for its distribution.
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