INVESTOR OVERVIEW

Spectral is seeking U.S. FDA approval for its lead product, Toraymyxin, a treatment for severe sepsis and septic shock. Toraymyxin is a therapeutic hemoperfusion device that removes endotoxin, the most important microbial trigger for sepsis, from the bloodstream. Directed by the Company’s Endotoxin Activity Assay (EAA™), the only FDA cleared, CE marked diagnostic for the detection of endotoxin, Spectral’s EUPHRATES trial is the world’s first theranostics trial in the area of sepsis.
Toraymyxin was approved for therapeutic use in Japan in 1994 and Europe in 2002 and has been used safely and effectively in more than 340,000 patients worldwide. In March 2009 and November 2010 respectively, Spectral obtained the exclusive development and commercial rights in the U.S. and Canada for Toraymyxin.
More than 1.7 million patients in the United States are diagnosed with sepsis each year. Approximately one third of these patients progress to severe sepsis and septic shock, representing a significant unmet need and an approximately $1.5 billion market opportunity for Spectral.
Spectral continues to provide high quality reagents in which royalty revenue is earned from license for the Company’s proprietary Troponin I and other reagent technologies. License arrangements are held with industry leaders.
Annual General Meeting
VIRTUAL AGM
June 7, 2023 at 4:00 PM ET
Following the completion of the Meeting, we’ll have a question and answer session. Please use the Audio Q&A link on your screen, under the Documents tab, to dial in and access the Q&A phone line. Once you are on the Q&A phone line, to ask a question during the session you will need to press Star One One on your telephone. You will then hear an automated message advising your hand is raised.
Annual General Meeting 2023 Presentation
Annual General Meeting Audio Replay
Management Information Circular
Presentations
Investor Update
Events & Webcasts
APAC 2023
Dr. Kellum presenting on numerous topics at The 5th Asia Pacific Acute Kidney Injury & Continuous Renal Replacement Therapy Congress (APAC) including Septic Shock and the Tigris Trial
September 21 – 24, 2023, Daegu, Korea
Endotoxic Septic Shock featured on The Balancing Act airing on Lifetime TV
Sepsis Alliance Summit Sponsored Session: What is Endotoxin and Why is it Important?
Debra Foster, BSc
Wednesday September 27, 2023 | 1:40pm ET PST
Sepsis Alliance Sponsor Innovation Webinar: Precision Medicine for Sepsis: Targeted Therapy Based on Molecular Endotyping
Thursday September 30, 2021 @2:oopm EST / 11:00am PST
Watch the replay.
vicenza course 2022
40th Vicenza Course on Acute Kidney Injury (AKI) and Continuous Renal Replacement Therapy (CRRT)
Symposium:
Endototoxemia in the Critically Ill and the Role of Polymyxin B Hemoperfusion
vicenza course 2021
39th Vicenza Course on Acute Kidney Injury (AKI) and Continuous Renal Replacement Therapy (CRRT)
Meet the Expert:
Biomarkers (EAA) – Guided Initiation of PMX Hemoperfusion in Sepsis
Symposium:
Endotoxic Shock: From Pathophysiology to Advanced Targeted Solutions
Cappuccino with Claudio Ronco:
CRRT Technology Update
vicenza course 2020
38th Vicenza Course on Acute Kidney Injury (AKI) and Continuous Renal Replacement Therapy (CRRT)
Cappuccino with Claudio Ronco
SAMI, an innovative platform for CRRT
Meet the Expert
Web Symposium
Meet the Expert
PARADIGM CAPITAL
Tel: 416.361.9080 Email: smcauley@paradigmcap.com