PUBLICATIONS
Polymyxin B haemoadsorption in endotoxic septic shock (Tigris): a multicentre, open-label, Bayesian, randomised, controlled, phase 3 trial
Prof Javier A Neyra, MD ∙ Prof Matthieu Legrand, MD ∙ Prof Mark A Tidswell, MD ∙ Prof Ali Al-Khafaji, MD ∙ Claude Galphin, MD ∙ Ronald Rains, MD et al.
The Lancet, March 2026
Organ Failure, Endotoxin Activity, and Mortality in Septic Shock
Molinari, Luca MD; Tidswell, Mark A. MD; Al-Khafaji, Ali MD, MPH; Davison, Danielle MD; Galphin, Claude MD; Kamaluddin, Esha HBSc; Foster, Debra M. BSc; Kellum, John A. MD
Critical Care Explorations 7(9):p e1308, September 2025.
Endotoxic Septic Shock: Diagnosis and Treatment
Foster DM, Kellum JA.
Int. J. Mol. Sci. 2023 Nov, 24, 16185.
Adsorption of endotoxin and mitigation of sepsis.
Kellum JA, Shoji H, Foster D, Walker PM.
Contrib Nephrol. 2023 Nov; 200:133-141.
Bayesian methods: a potential path forward for sepsis trials.
Tomlinson, G., Al-Khafaji, A., Conrad, S.A. et al.
Crit Care 27, 432 (November 2023).
Endotoxemia Correlates with Kidney Function and Length of Stay in Critically Ill Patients.
Piret SE, Khan S, Fairuz F, et al.
Blood Purif. 2023 Nov 2:1-10.
The role of endotoxin in septic shock.
Kellum JA, Ronco C.
Crit Care. 2023 Oct 19;27(1):400.
Targeted therapy using polymyxin B hemadsorption in patients with sepsis: a post-hoc analysis of the JSEPTIC-DIC study and the EUPHRATES trial.
Osawa I, Goto T, Kudo D, et al.
Crit Care. 2023 Jun 21;27(1):245.
Rationale for sequential extracorporeal therapy (SET) in sepsis.
Ronco C, Chawla L, Husain-Syed F, Kellum JA.
Crit Care. 2023 Feb 7;27(1):50.
Endotoxemic Shock: A Molecular Phenotype in Sepsis.
Kellum JA, Foster D, Walker PM.
Nephron. 2023 Feb ;147(1):17-20.
Increased Endotoxin Activity in COVID-19 Patients Admitted to the Intensive Care Unit.
Dela Cruz PTH, Davison D, Yamane DP, Chu E, Seneff M.
J Intensive Care Med. 2023 Jan;38(1):27-31.
Endotoxemic Sepsis: Clinical Features and Therapy.
Kellum JA, Shoji H, Foster D, Walker PM.
Journal of Translational Critical Care Medicine 2022 December;4:13.
Endotoxemic Sepsis: Clinical Features and Therapy.
Kellum JA, Shoji H, Foster D, Walker PM.
Journal of Translational Critical Care Medicine 2022 December;4:13.
Endotoxemia in Critically Ill Patients with COVID-19.
Khan S, Bolotova O, Sahib H, Foster D, Mallipattu SK.
Blood Purif. 2022 June ;51(6):513-519.
Subtypes and Mimics of Sepsis.
Kellum JA, Formeck CL, Kernan KF, Gómez H, Carcillo JA.
Crit Care Clin. 2022 April 38(2):195-211.
Endotoxin Adsorbent Therapy in Severe COVID-19 Pneumonia.
Peerapornratana S, Sirivongrangson P, Tungsanga S, et al.
Blood Purif. 2022 Jan ;51(1):47-54.
Extracorporeal Blood Purification and Organ Support in the Critically Ill Patient during COVID-19 Pandemic: Expert Review and Recommendation.
Ronco C, Bagshaw SM, Bellomo R, et al.
Blood Purif. 2021 50(1):17-27.
Endotoxemia and circulating bacteriome in severe COVID-19 patients.
Sirivongrangson P, Kulvichit W, Payungporn S, et al.
Intensive Care Med Exp. 2020 Dec 7;8(1):72.
Intervening in Sepsis: Can Nurses Do More?
Updated guidelines may help nurses identify sepsis quicker and treat it more efficiently
Debra M. Foster
Healthcare Network for Nurses January 2017
Role of Technology for the Management of AKI in Critically Ill Patients: From Adoptive Technology to Precision Continuous Renal Replacement Therapy
Cerdá J., Baldwin I., Honore P.M., Villa G., Kellum J.A., Ronco C.
Blood Purification Vol. 42, No. 3, September 2016
Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry
Salvatore Lucio Cutuli, Antonio Artigas, Roberto Fumagalli, Gianpaola Monti, Vito Marco Ranieri, Claudio Ronco, Massimo Antonelli.
Annals of Intensive Care, August 2016
Elevated Serum PCT in Septic Shock With Endotoxemia Is Associated With a Higher Mortality Rate.
Adamik B, Smiechowicz J, Jakubczyk D, Kubler A
Medicine 2015 July, 94(27):e1085.
Endotoxin Removal: Bringing the Mission to North America
Foster D., Klein D.J,. Guadagni G.,Walker P.M.
Blood Purification, Vol. 37, Suppl. 1, January 2014